Bitter Melon (Momordica charantia) is a tropical fruit or gourd that grows on a green leafed vine. It is native to Africa, Asia, Central America, and South America, and has been used in those areas for the treatment of hyperglycemia. Bitter melon has natural hypoglycemic properties. The seeds contain polypeptides and charantin. These compounds have been reported to have sugar regulation qualities, as they are similar in structure to bovine insulin. There’s no clear standard dosing for bitter melon. You can eat a fresh melon daily or drink the juice of the fruit. Powdered extracts are available in doses ranging from 3 to 15 g/day.